根据西班牙的严重程度,慢性鼻炎没有/有鼻的患病率
J Mullol1, J Sastre2, J Dominguez-Ortega3
1Rhinology Unit and Smell Clinic, ENT Department, Hospital Clinic, Universitat de Barcelona, FRCB-IDIBAPS, CIBERES, Barcelona, Catalonia, Spain.
慢性鼻炎 (CRS) 影响了西班牙5.1%的人口. 有鼻息肉的严重慢性鼻炎 (CRSwNP) 更常见,与2型炎症有关,尽管没有鼻息肉的慢性鼻炎 (CRSsNP) 更普遍.
科学领域:
- 耳鼻喉科 耳鼻喉科 耳鼻喉科
- 流行病学 流行病学
- 免疫学 免疫学 免疫学
背景情况:
- 慢性鼻炎 (CRS) 影响全球5-12%,其中20%患有鼻.
- 对于西班牙的CRS存在有限的流行病学数据.
- 这项研究调查了西班牙的CRS患病率,严重程度和同时存在的2型炎症性疾病.
研究的目的:
- 为了确定西班牙有 (CRSwNP) 和没有 (CRSsNP) 鼻息肉的CRS的患病率和严重程度.
- 分析CRS严重程度与2型炎症疾病之间的关联.
- 为西班牙人口提供CRS的流行病学见解.
主要方法:
- 使用BIG-PAC®数据库进行了回顾性,全国性的流行病学研究.
- 使用特定的诊断代码识别了CRSsNP和CRSwNP患者.
- 根据抗生素疗程,皮质类固醇使用或之前的鼻手术来确定疾病的严重程度.
主要成果:
- 在超过100万名患者中,西班牙的整体CRS患病率为5.1% (4.3%CRSsNP,0.8%CRSwNP).
- 在CRSwNP患者中,严重的CRS形式更频繁.
- 与CRSsNP相比,CRSwNP患者表现出较高的年龄和较高的2型炎症生物标志物.
结论:
- 在西班牙,CRSsNP比CRSwNP更为普遍.
- 严重的CRS在CRSwNP患者中更为常见.
- CRSwNP与同时存在的2型炎症性疾病的更高发病率有关.
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