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基于智能手机的视频观察治疗与基于社区的直接观察治疗下的结核病治疗合规性:集群随机对照试验

Ponlagrit Kumwichar¹, Tagoon Prappre¹, Virasakdi Chongsuvivatwong¹

¹Department of Epidemiology, Faculty of Medicine, Prince of Songkla University, Hat Yai, Thailand.

JMIR mHealth and uHealth

|June 3, 2024

概括

视频观察疗法 (VOT) 显示出比直接观察疗法 (DOT) 更高的观察者遵守结核病治疗. 然而,这项研究缺乏证实患者遵守或唾液转化率差异的能力.

科学领域:

公共卫生公共卫生
传染性疾病传染性疾病
临床试验临床试验

背景情况:

最近对结核病 (TB) 治疗中的患者和观察者遵守率进行了有限的研究,比较了视频观察治疗 (VOT) 和直接观察治疗 (DOT).
这项研究解决了对VOT和DOT计划之间的合规性和处理结果的比较数据的需求.

研究的目的:

为了比较VOT和DOT之间的肺结核治疗患者和观察者合规率.
通过VOT与DOT接受结核病治疗的患者之间的唾液转化率进行比较.

主要方法:

一项为期60天的集群随机对照试验比较了VOT (基于智能手机的视频提交) 与DOT (标准程序) 在肺结核患者中具有阳性唾液涂抹.
该试验包括VOT组的63名患者和DOT组的65名患者,以及38名观察员 (每组19名).
治疗意图分析评估了患者和观察者遵守和唾液转化率.

主要成果:

与DOT相比,VOT在患者 (15.2天) 和观察者 (21.2天) 的平均遵守率显著更高.
唾液转换率为VOT的73%,为DOT的61.5%,尽管这种差异在统计学上并不显著 (P=.17).

结论:

与基于社区的DOT相比,基于智能手机的VOT显著改善了观察者对结核病治疗的遵守.
这项研究不足以最终得出改善患者服从性或VOT和DOT之间唾液转化率的显著差异的结论.

关键词:

数字健康数字健康医疗保健系统医疗保健系统肺部疾病肺部疾病手机电话手机电话手机电话观察到的治疗方法.随机化试验是一种随机化试验.远程医疗服务是远程医疗服务.远程医疗远程医疗治疗合规性的治疗方法结核病是一种肺结核病.视频增强疗法视频增强疗法

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