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Updated: Jun 24, 2025

SorLA and CLC:CLF-1-dependent Downregulation of CNTFRα as Demonstrated by Western Blotting, Inhibition of Lysosomal Enzymes, and Immunocytochemistry
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SorLA and CLC:CLF-1-dependent Downregulation of CNTFRα as Demonstrated by Western Blotting, Inhibition of Lysosomal Enzymes, and Immunocytochemistry

Published on: January 6, 2017

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索洛林是WAPL的一个进化保守的对手

Ignacio Prusén Mota1,2,3, Marta Galova4, Alexander Schleiffer4

  • 1Max Perutz Labs, Vienna Biocenter Campus (VBC), Vienna, Austria.

Nature communications
|June 3, 2024
PubMed
概括

索洛林对抗WAPL以保护凝聚素,这对染色体分离和DNA修复至关重要. 这项研究在酵母和植物中发现SORORIN,揭示了它在体内保存和组织特异性的作用.

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