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Updated: Jun 24, 2025

A Scalable, Cell-Based Method for the Functional Assessment of Ube3a Variants
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A Scalable, Cell-Based Method for the Functional Assessment of Ube3a Variants

Published on: October 10, 2022

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在UNC93B1的遗传变异倾向于儿童开始的系统性红血性狼

Mahmoud Al-Azab1,2, Elina Idiiatullina1,3, Ziyang Liu1

  • 1Department of Immunology, Guangzhou Institute of Paediatrics, Guangzhou Women and Children's Medical Centre, and State Key Laboratory of Respiratory Diseases, Guangzhou Medical University, Guangzhou, China.

Nature immunology
|June 3, 2024
PubMed
概括

在UNC93B1中的新遗传变异,一种调节收费类受体7 (TLR7) 的蛋白质,与儿童发病的系统性红斑狼有关. 这些变体会引起过度活跃的免疫反应,导致狼的发展.

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