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Updated: May 12, 2026

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Vidyani Suryadevara1, Adam D Hudgins2, Adarsh Rajesh3

  • 1Department of Radiology, Molecular Imaging Program at Stanford (MIPS), Stanford University, School of Medicine, Stanford, CA, USA.

Nature reviews. Molecular cell biology
|June 3, 2024
PubMed
概括

细胞衰老,曾经被认为是实验室的工件,现在在组织中得到了认可. 这项研究为在各种组织中识别衰老细胞提供了指导方针,有助于研究这种复杂的生物过程.

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Replicative Cell Senescence02:15

Replicative Cell Senescence

Replicative cell senescence is a property of cells that allows them to divide a finite number of times throughout the organism's lifespan while preventing excessive proliferation. Replicative senescence is associated with the gradual loss of the telomere — short, repetitive DNA sequences found at the end of the chromosomes. Telomeres are bound by a group of proteins to form a protective cap on the ends of chromosomes. Embryonic stem cells express telomerase — an enzyme that adds the telomeric...