通过NF-κB途径,通过TgCtwh3诱导的神经元亡的DJ-1加剧神经元亡

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Updated: Jun 24, 2025

High Content Screening in Neurodegenerative Diseases
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Published on: January 6, 2012

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Di Yang1, Minmin Wu2, Nian Zou3

  • 1Department of Pathogen Biology, Anhui Province Key Laboratory of Microbiology & Parasitology, Anhui Provincial Laboratory of Zoonoses of High Institutions, School of Basic Medicine, Anhui Medical University, Hefei, China.

Molecular neurobiology
|June 3, 2024
PubMed
概括

在Toxoplasma gondii感染期间,DJ-1蛋白水平下降,导致神经元亡. 击败DJ-1通过NF-κB通路加剧了这种细胞死亡,突出了DJ-1作为T. gondii诱导的神经退行症的目标.

关键词:
细胞灭亡 (apoptosis) 是一种死亡的过程.在DJ-1中,DJ-1是DJ-1.海马神经元中的神经元.这就是NF-κBB.TgCtwh3是什么意思

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