局部类固醇注射作为食道内镜下粘膜解剖后电凝综合征的危险因素
Yuri Kim1, Hee Kyong Na2, Ji Yong Ahn2
1Division of Gastroenterology, Department of Internal Medicine, Keimyung University Dongsan Hospital, Keimyung University School of Medicine, Daegu, Korea.
后内镜下粘膜解剖电凝综合征 (PEECS) 影响了近一半接受食道内镜下粘膜解剖 (ESD) 的患者. 大型瘤和较长的手术增加了PEECS风险,而局部类固醇注射可能会减少它.
科学领域:
- 胃肠病学 胃肠病学
- 内镜检查是指内镜检查.
- 在瘤学瘤学.
背景情况:
- 后内镜下粘膜剖析电凝综合征 (PEECS) 是食道瘤内镜下粘膜剖析 (ESD) 后的常见并发症.
- 关于PEECS发病率和风险因素的数据有限,因为定义不清楚,临床环境不同.
研究的目的:
- 为了确定与PEECS相关的风险因素,在接受ESD因食道瘤的患者中.
主要方法:
- 对202名接受食道ESD治疗的患者进行了回顾性审查.
- 在ESD后24小时内,发烧,白细胞体或胸痛定义的PEECS.
- 通过回归分析确定的风险因素.
主要成果:
- 在48.5%的患者中发生了PEECS.
- 风险因素包括较大的瘤大小 (≥17毫米),较长的手术时间 (≥33分钟) 和较长的静血时间 (≥5分钟).
- 局部类固醇注射与PEECS有负面关联.
结论:
- 患有大型瘤和延长手术/静血时间的患者患PEECS的风险更高.
- 局部类固醇注射可能是防止PEECS的保护因素.
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