结直肠癌后的自杀 - - 一项基于全国人口的研究
Charlotta Larsson1,2, Hanna de la Croix2,3, Rode Grönkvist1,4
1Department of Surgery, SSORG - Scandinavian Surgical Outcomes Research Group, Institute of Clinical Sciences, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.
概括
患有结直肠癌的患者自杀的风险几乎翻了一番,尤其是男性. 没有手术的患者面临7倍的增加,强调了有针对性的心理健康支持的需要.
科学领域:
- 在瘤学瘤学.
- 精神病学是一个精神病学.
- 公共卫生 公共卫生
背景情况:
- 结肠直肠癌的诊断与显著的情绪痛苦有关.
- 之前的研究表明,癌症患者的自杀风险较高.
研究的目的:
- 确定新诊断的结肠直肠癌患者中自杀的发生率.
- 为了比较结直肠癌患者的自杀率与匹配的对照组.
主要方法:
- 使用了结直肠癌患者的国家瑞典队列 (CRCBaSe) 和匹配的对照.
- 采用Cox的比例风险模型来分析自杀死亡率,调整风险因素.
主要成果:
- 对结直肠癌进行手术的患者,在诊断后的第一年,自杀风险比率增加1.86倍.
- 男性的自杀风险 (HR 2.08) 比女性 (HR 1.09) 高.
- 没有手术的结直肠癌患者的自杀风险增加了七倍 (HR 7.03).
结论:
- 结肠直肠癌患者,特别是男性,在手术后面临着明显更高的自杀风险.
- 没有手术的患者表现出明显增加的自杀风险,这表明需要增加资源和支持.
- 早期识别结直肠癌患者的自杀风险因素至关重要.
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