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Updated: Jun 24, 2025

Induction and Analysis of Epithelial to Mesenchymal Transition
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Published on: August 27, 2013

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缺氧-表观遗传轴驱动胰腺癌中的EMT

Matthias Wirth1,2,3,4, Günter Schneider1,5,6

  • 1Department of General, Visceral and Pediatric Surgery, University Medical Center Göttingen, Göttingen, Germany.

Cancer research
|June 4, 2024
PubMed
概括

在胰腺癌中,低氧会通过改变基因组甲基化来触发上皮细胞到介质细胞的转换 (EMT). 这项研究揭示了缺氧诱导的信号如何调节H3K36me2标记,影响癌细胞的可塑性.

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