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吸烟对南非人口口腔微生物群的影响,使用下膜斑样本
Yvonne Prince1, Glenda M Davison1, Saarah F G Davids1
1SAMRC/CPUT/Cardiometabolic Health Research Unit, Department of Biomedical Sciences, Faculty of Health and Wellness Sciences, Cape Peninsula University of Technology, Bellville, South Africa.
Heliyon
|June 4, 2024
概括
吸烟显著改变了口腔微生物群,减少了有益的活性细菌,增加了有害的无氧细菌. 口腔细菌的这种转变可能使吸烟者易患牙周病.
科学领域:
- 微生物学 微生物学
- 口腔健康 口腔健康
- 基因组学就是基因组学.
背景情况:
- 口腔微生物群的干扰与吸烟和牙周病有关.
- 口腔细菌的不平衡会影响天生的免疫系统.
研究的目的:
- 在南非调查吸烟者与非吸烟者之间的口腔微生物群差异.
- 为了识别受吸烟影响的特定细菌种群.
主要方法:
- 从128名参与者 (57名吸烟者) 收集了下斑块样本.
- 使用16S rRNA基因测序分析了口腔微生物组合.
- 吸烟者通过血清中胆固醇水平 (>15 ng/ml) 来识别.
主要成果:
- 在吸烟者和非吸烟者之间观察到口腔微生物群的显著差异.
- 吸烟者表现出减少了Actinobacteria的丰富性.
- 在吸烟者中,Fusobacterium和Campylobacter的丰度增加,Leptotrichia,Actinomyces,Corynebacterium和Lautropia的丰度减少. 在吸烟者中,Fusobacterium和Campylobacter的丰度增加,以及Leptotrichia,Actinomyces,Corynebacterium和Lautropia的丰度减少.
结论:
- 吸烟会改变口腔微生物群,有利于无氧性阴性细菌.
- 这些微生物转移可能会增加对牙周病发展和进展的敏感性.
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