探索不同品种Brassica oleracea的抗菌潜力和细胞毒性作用
Kavishri S1, Suganya Panneer Selvam1, Rajeshkumar Shanmugam2
1Oral Biology, Saveetha Dental College and Hospitals, Saveetha Institute of Medical and Technical Sciences, Saveetha University, Chennai, IND.
Cureus
|June 4, 2024
概括
来自Brassica oleracea的红菜提取物显示出强大的抗菌特性,可以对抗口腔病原体,如Candida albicans和Streptococcus mutans. 这种天然化合物显示出开发新的牙卫生产品以打击牙的前景.
科学领域:
- 口腔健康 口腔健康
- 自然产品 化学 化学
- 微生物学 微生物学
背景情况:
- 牙损是一个重大的全球健康挑战.
- 布拉西卡菜 (白菜) 含有维生素C,K和E,以抗生素和抗氧化剂的特性而闻名.
- 这些特性可以保护口腔免受病原体的影响,建议在牙科配方中使用.
研究的目的:
- 为了评估Brassica oleracea提取物的抗菌和细胞毒性作用.
- 为了确定红菜和绿菜提取物对口腔微生物的疗效.
- 评估Brassica oleracea作为牙科产品中的天然成分的潜力.
主要方法:
- 准备了Brassica oleracea (红菜和绿菜) 的提取物.
- 通过对Candida albicans,Enterococcus faecalis和Streptococcus mutans进行区域抑制试验来评估抗菌活性.
- 细胞毒性是通过在不同度下使用nauplii试验来评估的.
主要成果:
- 与绿菜提取物相比,红菜提取物表现出优越的抗菌活性.
- 红菜提取物表现出针对Candida albicans (20毫米),Enterococcus faecalis (15毫米) 和Streptococcus mutans (9毫米) 的显著抑制区域.
- 两种提取物都显示出更高度的细胞毒性增加,在20μL时观察到最大毒性.
结论:
- 布拉西卡 (Brassica oleracea) 提取物具有显著的抗菌特性,对口腔健康有益.
- 这些发现支持将Brassica oleracea纳入牙膏和口水等牙科产品.
- 该研究强调了一种天然,有效的替代方案,用于预防口腔感染和促进口腔卫生.
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