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Updated: Jun 24, 2025

Artificial RNA Polymerase II Elongation Complexes for Dissecting Co-transcriptional RNA Processing Events
10:59

Artificial RNA Polymerase II Elongation Complexes for Dissecting Co-transcriptional RNA Processing Events

Published on: May 13, 2019

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一个工程T7RNA聚合酶,用于在mRNA合成中减少dsRNA副产品的高效协同转录封锁

Mathew Miller1, Oscar Alvizo1, Scott Baskerville1

  • 1Codexis, Inc., 200 Penobscot Drive, Redwood City, CA 94063, USA. justin.dassie@codexis.com.

Faraday discussions
|June 4, 2024
PubMed
概括

制造信使RNA (mRNA) 疗法是一项挑战. 一个新的酶,T7-68,改善了盖子模拟的结合,并减少了不必要的双链RNA (dsRNA) 副产品,以获得更可行的mRNA治疗方法.

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