相关实验视频
Updated: Jun 24, 2025

Blind Endotracheal Intubation in Neonatal Rabbits
Published on: February 26, 2021
一种用于新生儿输入腹腔管的止痛技术:DOLATSONG,一个随机的多中心控制试验
Hélène Darretain1, François-Xavier Laborne, Steven Lagadec
1Author Affiliations: Medicine and Neonatal Intensive Care Unit, Centre Hospitalier Sud Francilien, Corbeil Essonnes, France (Mss Darretain and Galand and Drs Granier and Razafimahefa); Medicine and Neonatal Intensive Care Unit, Saint Joseph Hospital, Paris, France (Dr Walter-Nicolet); INSERM, U1153, Epidemiology and Statistics, Sorbonne Paris Cité Research Center, Obstetrical, Perinatal and Pediatric Epidemiology Team, Paris, France (Dr Walter-Nicolet); Medicine and Neonatal Intensive Care Unit, Hôpital Delafontaine, Saint-Denis, France (Drs Harbi and Waszak); SAMU 91, Centre Hospitalier Sud Francilien, Corbeil Essonnes, France (Dr Laborne and Messrs Lagadec and Garrigue); Clinical Research Unit, Centre Hospitalier Sud Francilien, Corbeil Essonnes, France (Dr Laborne and Messrs Lagadec and Garrigue); and CNRD, Hôpital Armand Trousseau (APHP), Paris, France (Dr Maillard).
一种通过瓶插入口胃管的新技术显著减少了新生儿的疼痛. 这种简单的方法提供了一种可行的方法来管理新生儿重症监护期间的手术疼痛.
科学领域:
- 新生儿护理 新生儿护理
- 儿科疼痛管理 儿科疼痛管理
- 医疗器械创新 医疗器械创新
背景情况:
- 胃管插入是新生儿在新生儿重症监护室的常见,痛苦的手术.
- 对于新生儿手术疼痛,存在有限的止痛选择.
- 需要新的方法来减少插入口胃管时的疼痛.
研究的目的:
- 评估一种新的口胃管插入技术.
- 为了确定通过瓶插入管子是否可以减少新生儿的疼痛.
- 将实验技术与标准方法进行比较.
主要方法:
- 一个前性的,随机的,受控的多中心研究.
- 新生儿 (怀孕≥32周) 接受了通常的或实验性的输入管技术.
- 通过视频分析,使用新生儿急性疼痛 (APN) 尺度来评估疼痛.
主要成果:
- 实验技术 (导管穿过乳头) 导致新生儿经历高疼痛得分的人数显著减少 (71.4%对41%,P = .031).
- 修改后的技术是预防疼痛的独立因素 (OR = 0.21,P = .015).
- 嘴频繁发生,但在不同组之间没有显著差异.
结论:
- 通过瓶插入口胃管是一种简单,廉价和可行的方法.
- 这种技术有效地限制了与新生儿的口胃管插入相关的疼痛.
- 这些发现支持采用这种技术来治疗新生儿疼痛.
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