在创伤性脑损伤中评估和药理学管理帕洛克性交感性过度活跃
Jamie L Ott1,2, Thomas K Watanabe1,2
1Author Affiliations: Department of Physical Medicine and Rehabilitation, University of Washington, Seattle, WA, (Dr Ott); and Drucker Brain Injury Center, Stroke Rehabilitation Program, Jefferson Moss-Magee Rehabilitation, Elkins Park, PA, (Dr Watanabe).
The Journal of head trauma rehabilitation
|June 4, 2024
概括
在严重创伤性脑损伤 (TBI) 中, Paroxysmal Sympathetic Hyperactivity (PSH) 需要一个多方面的管理方法. 本指南提供了对同情和肌肉骨症状的实际干预措施,以帮助临床决策.
科学领域:
- 神经科学是一个神经科学.
- 临界护理医学 临界护理医学
- 药理学 药理学是指药理学的学科.
背景情况:
- 发性交感性多动性 (PSH) 影响高达10%的严重创伤性脑损伤 (TBI) 患者.
- PSH与患者不良结果有关,但缺乏对管理的共识.
- 对PSH管理的结构化方法对于改善患者预后至关重要.
研究的目的:
- 为 PSH 在 TBI 中提供实用,多方面的临床管理指南.
- 审查PSH的药理,程序和非药理干预措施.
- 突出治疗PSH的交感和肌肉骨表现的药物治疗策略.
主要方法:
- 审查关于PSH管理策略的当前文献.
- 包括关于新型临床管理方法的最新研究.
- 强调用于PSH评估的标准化评估工具.
主要成果:
- 讨论治疗交感和肌肉骨症状的药理选择.
- 在PSH治疗范式中整合疼痛管理.
- 在选择治疗时考虑药物的副作用.
结论:
- 对于PSH,药理学数据有限,需要临床方法.
- 干预选择应以主要症状 (交感性过动,疼痛,肌肉高) 为指导.
- 建议根据症状表现和药物的副作用概况量身定制治疗.
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