皮层区域的原理及其对神经成像的影响
Steven E Petersen1, Benjamin A Seitzman2, Steven M Nelson3
1Mallinckrodt Institute of Radiology, Washington University School of Medicine, St. Louis, MO 63110, USA; Department of Neurology, Washington University School of Medicine, St. Louis, MO 63110, USA; Department of Biomedical Engineering, Washington University in St. Louis, St. Louis, MO 63130, USA; Department of Psychological and Brain Sciences, Washington University in St. Louis, St. Louis, MO 63130, USA; Department of Pediatrics, Washington University School of Medicine, St. Louis, MO 63110, USA.
皮层区域化,大脑中的大脑.
科学领域:
- 神经科学是一个神经科学.
- 认知神经科学 认知神经科学
背景情况:
- 皮层组织对于理解大脑在行为和认知中的功能至关重要.
- 区域化,即离散皮层区域的概念,是皮层组织的核心原则.
研究的目的:
- 通过非人类动物研究来阐明皮层区域化原理的审查.
- 讨论这些原则在神经成像研究中的应用.
- 突出可能违反实现原则的神经成像数据的解释.
主要方法:
- 对非人类动物研究的审查,以定义皮质区域,它们的形成,相互作用和功能.
- 对神经成像研究的分析,根据皮层区域化的既定原则.
主要成果:
- 非人类动物研究揭示了定义,形成和功能性特征皮质区域的关键原则.
- 神经成像解释通常依赖于与区域化原则相冲突的假设 (例如,非静止区域,单一功能).
结论:
- 从神经生物学得出的原则应该指导对大脑功能的计算解释.
- 需要对神经成像解释进行重新评估,以与已建立的皮质组织原则保持一致.
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