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Updated: Jun 24, 2025

A RAPID Method for Blood Processing to Increase the Yield of Plasma Peptide Levels in Human Blood
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吉雷德斯特兰特的质量平衡,代谢途径,绝对生物可用性和健康人群中的药理动力学

Smita Kshirsagar1, Ya-Chi Chen1, Jiajie Yu1

  • 1Clinical Pharmacology (S.K., Y.-C.C., J.Y., S.Ka., L.M., V.M.), Drug Metabolism and Pharmacokinetics (S.C.K., S.M., J.W., S.C., Y.T., D.Z., W.Z., T.DB.), Early Clinical Development and Oncology (M.R.G.), and Safety Science (U.O.), Genentech, Inc., South San Francisco, California.

Drug metabolism and disposition: the biological fate of chemicals
|June 4, 2024
PubMed
概括

吉雷德斯特兰是一种新型雌激素受体降解剂,在人类中表现出适度的口服生物利用性. 药物主要通过氧化代谢和便分泌而排出.

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