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Updated: Jun 24, 2025

Sample Extraction and Simultaneous Chromatographic Quantitation of Doxorubicin and Mitomycin C Following Drug Combination Delivery in Nanoparticles to Tumor-bearing Mice
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密集剂量多克索鲁比加环胺在修改的KEYNOTE522治疗三阴性乳腺癌的方案中

Nicholas Mai1, Sara Myers2, Sherry Shen1

  • 1Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA.

NPJ breast cancer
|June 4, 2024
PubMed
概括

在新辅助剂KEYNOTE-522治疗三阴性乳腺癌 (TNBC) 的方案中,剂量密集的多克索鲁比加环胺 (ddAC) 是安全有效的. 化疗序列并没有影响病理完整反应,但ddAC首先增加了治疗延迟和细胞衰竭.

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