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PARP14受PARP9/DTX3L复合体的调节,并促进干扰素γ诱导的ADP-ribosylation

Victoria Chaves Ribeiro1, Lilian Cristina Russo1, Nícolas Carlos Hoch2

  • 1Department of Biochemistry, University of São Paulo, São Paulo, 05508-000, Brazil.

The EMBO journal
|June 4, 2024
PubMed
概括

主体ADP-ribosylation对于抗病毒防御至关重要,由PARP14和PARP9/DTX3L复合体进行介导. SARS-CoV-2 Nsp3通过水解ADP-ribosylation修饰来对抗这种宿主反应.

关键词:
在ADP-Ribosylation过程中.新冠病毒新冠病毒新冠病毒.具有天生的免疫力.干扰素 干扰素 干扰素在PARP中,PARP是PARP.

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