父母报告的第一个牙出现时间和ECC的关联:对病例控制研究的二次分析
概括
幼儿早期牙喷发与儿童早期牙 (ECC) 的更高风险有关. 报告说在六个月前出现了第一个牙的父母表明,ECC发育的可能性显著增加.
科学领域:
- 儿科牙科 儿科牙科
- 公共卫生 公共卫生
- 发展生物学 发展生物学
背景情况:
- 幼儿 (ECC) 是一个重大的全球公共卫生挑战.
- 牙喷发的时间可以作为发育过程的指标.
- 了解与ECC风险相关的因素对于早期干预至关重要.
研究的目的:
- 调查第一个初始牙出现的时间与幼儿ECC患病率之间的关联.
- 确定早期牙喷发是否是ECC的危险因素.
主要方法:
- 从一个病例控制研究中对627名幼儿的二次数据分析.
- 根据父母报告的第一个牙的出现 (在6个月前,7-9个月,10-12个月,12个月后) 儿童被分为四组.
- 单变二进制物流回归用于评估喷发时间和ECC之间的关系.
主要成果:
- 在6个月前第一个牙喷发的幼儿中,ECC的患病率明显更高 (12%的病例与8%的对照).
- 在早期牙出现 (6个月前) 的儿童中,观察到ECC的几率比为3.5 (95%CI1.49,8.42).
- 早期爆发与较高比例的腐烂前牙相关,而延迟爆发则显示较低比例的腐烂后牙.
结论:
- 父母报告的第一个母牙的早期出现与患儿早期牙的风险增加有关.
- 牙喷发的时间可以作为ECC风险评估的早期临床标志物.
- 进一步的研究可以探索与早期爆发和ECC易感性相关的潜在机制.
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