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Updated: Jun 24, 2025

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使用深度学习方法改善N-carbamoyl酸酶的酶活性和稳定性

Fa Zhang1,2, Muhammad Naeem1, Bo Yu2

  • 1College of Life Science, Hebei Normal University, Shijiazhuang, 050024, China.

Microbial cell factories
|June 4, 2024
PubMed
概括

研究人员开发了"Feitian"软件,通过增强DCase酶活性和稳定性来改善D-氨基酸生产. 一个三点突变 (DCase-M3) 显示显著提高了性能,为工业D-氨基酸合成铺平了道路.

关键词:
D-p-hydroxyphenylglycine 是一种基的化合物.深度学习模块深度学习模块分子动力学模拟模型氨基酸氨基基基氨基酸氨基基氨基酶的N-carbamoyl-D氨基酸.理性的设计理性的设计.

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