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Updated: Jun 24, 2025

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单细胞RNA测序揭示了ICP和正常怀孕期间母胎界面的异质性和差异表达

Xianxian Liu1, Siming Xin1, Fangping Xu1

  • 1Key Laboratory of Women's Reproductive Health of Jiangxi Province, Jiangxi Maternal and Child Health Hospital, Nanchang, Jiangxi, China.

The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians
|June 5, 2024
PubMed
概括

怀孕的肝脏内胆固醇症 (ICP) 改变胎盘细胞类型和基因表达,影响胎盘功能,并可能导致不良周产期结果. 这项研究揭示了与正常怀孕相比,ICP胎盘的细胞和遗传差异.

关键词:
在ICP中,ICP是指ICP.不同表达的基因.孕产妇和胎儿之间的接口.胎盘 胎盘 胎盘 胎盘一个单细胞RNA测序.

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RNA sequencing, or RNA-Seq, is a high-throughput sequencing technology used to study the transcriptome of a cell. Transcriptomics helps to interpret the functional elements of a genome and identify the molecular constituents of an organism. Additionally, it also helps in understanding the development of an organism and the occurrence of diseases. 
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