手术后恶心和吐在接受 laparoscopic 胃肠道手术的女性患者,并进行双重预防性治疗
Chunmeng Lin1,2, Jing Li2,3, Qian Wu2,4
1Department of Anesthesia, The Sixth Affiliated Hospital, Sun Yat-sen University, Guangzhou, China.
概括
手术后恶心和吐 (PONV) 在腹腔镜胃肠道手术后的女性患者中仍然很常见,即使是双重预防. 较高的摩剂量增加了PONV风险,而化疗史可能是保护性的.
科学领域:
- 麻醉学 麻醉学
- 胃肠道手术 胃肠道手术
- 在瘤学瘤学.
背景情况:
- 手术后恶心和吐 (PONV) 是手术后的一种严重并发症.
- 有效的PONV预防对于患者的康复和满意度至关重要.
- laparoscopic胃肠道手术对PONV管理提出了独特的挑战.
研究的目的:
- 为了确定腹腔镜胃肠道手术的女性患者中PONV的发病率.
- 在这个患者群体中识别与PONV相关的因素.
- 在双重预防治疗方案 (帕洛诺塞和德克萨米他) 下评估PONV发病率.
主要方法:
- 对109名接受了palonosetron和dexamethasone用于PONV预防的女性患者进行了回顾性分析.
- 包括患者特征和术后管理因素.
- 单变量和多变量分析以确定PONV.影响因素.
主要成果:
- 在分析的105名患者中,PONV发生在50.5%的患者中.
- 化疗病史与PONV风险降低有关 (或0.325).
- 摩的剂量≥0.02 mg/kg与PONV风险增加有关 (或2.857).
结论:
- 在接受腹腔镜胃肠道手术的女性患者中,PONV的发病率很高,尽管进行了双重预防性治疗.
- 较高的摩剂量可能会增加PONV风险.
- 化疗史似乎是对PONV的保护因素.
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