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前列腺的跨膜活检不需要常规的抗生素覆盖

David Dryhurst¹, Abdullatif Aydin², Nkwam Nkwam³

¹Urology, Princess Royal University Hospital, King's College Hospital NHS Foundation Trust, London, GBR.

|June 5, 2024

概括

常规单剂量抗生素对跨关节前列腺活检 (TPB) 的并发症率没有影响. 这项研究发现,接受抗生素和不接受抗生素的患者之间的活检后发病率没有显著差异,导致常规抗生素使用停止.

科学领域:

泌尿器科泌尿器科泌尿器科泌尿器科
传染性疾病传染性疾病
在瘤学瘤学.

背景情况:

经直肠超声导向前列腺活检 (TRUSB) 历来存在感染风险,需要抗生素预防.
在局部麻醉剂 (LA) 下的超膜超声导向前列腺活检 (TPB) 现在是诊断前列腺癌的首选方法.
对TPB的抗生素预防的必要性仍在调查中.

研究的目的:

为了确定单剂量口服抗生素是否会影响跨膜超声波引导前列腺活检 (TPB) 后的并发症率.

主要方法:

对326名连续接受TPB.患者的回顾性分析.
在接受单剂量口服抗生素 (co-amoxiclav 或 ciprofloxacin) 的队列和没有接受抗生素的队列之间比较并发症率.
排除持久导管或现有的尿路感染 (UTI) 的患者.

主要成果:

99.4%的患者没有出现术后并发症.
抗生素组中的两名患者 (1.1%) 患有传染性并发症 (前列腺,尿液过敏).
在没有抗生素的组中没有报告任何并发症;这种差异在统计学上并不显著 (p=0.50).

结论:

常规单剂量抗生素预防并不能降低跨膜超声波引导前列腺活检 (TPB) 后的发病率.
根据这些发现,该单位已经停止了LA TPB的常规抗生素覆盖.
这表明前列腺活检程序的抗生素管理可能发生转变.

关键词:

这就是AMR AMR.抗生素抗生素是一种抗生素.抗生素管理计划抗生素管理计划感染的感染感染.这是一种局部麻醉剂.前列腺癌是前列腺癌.这是一种血症.跨关腺前列腺活检跨直肠前列腺活检

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