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Updated: Jun 24, 2025

Probing RNA Structure with Dimethyl Sulfate Mutational Profiling with Sequencing In Vitro and in Cells
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Published on: December 9, 2022

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从RNA序列到其三维结构:SARS-CoV-2RNA的选定片段的几何结构,稳定性和动态

Leonid Gorb1, Ivan Voiteshenko1,2, Vasyl Hurmach1

  • 1Department of Molecular and Quantum Biophysics, Institute of Molecular Biology and Genetics, National Academy of Sciences of Ukraine, 150, Akademika Zabolotnoho Str., Kyiv 03143, Ukraine.

NAR genomics and bioinformatics
|June 5, 2024
PubMed
概括

这项研究通过计算模拟了SARS-CoV-2RNA结构,发现G-四重复是最稳定的. 反对子和侧面核酸显著影响RNA稳定性和键网络.

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