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在怀孕期间,介质干细胞对COVID-19的保护潜力在怀孕期间

Sihem Aouabdi^1,2, Doaa Aboalola^1,2, Samer Zakari^1,2

¹King Abdullah International Medical Research Center, Jeddah, 21423, Saudi Arabia.

Future science OA

|June 5, 2024

概括

介质细胞干细胞 (MSCs) 可能会保护孕妇免受严重的COVID-19感染. 这些细胞是这些细胞.

科学领域:

免疫学免疫学免疫学
病毒学病毒学
孕产妇和胎儿的医学

背景情况:

SARS-CoV-2 感染导致COVID-19,导致严重疾病和死亡率.
孕妇通常比非孕妇体验的COVID-19症状不那么严重.
细胞因子风暴和肺炎是严重COVID-19的关键病理特征.

研究的目的:

审查孕妇中孕妇血液中循环的胎儿介质干细胞 (MSCs) 对COVID-19的潜在保护作用.
探索MSCs在治疗SARS-CoV-2感染中的治疗潜力.

主要方法:

关于怀孕期间COVID-19的已发表报告的文献综述.
分析MSCs的免疫调节,抗炎和抗病毒特性.
对MSC的保护作用提出的机制的审查.

主要成果:

在孕妇血液中循环的胎儿介质干细胞 (MSC) 可能会减轻孕妇的COVID-19症状.
MSCs具有固有的免疫调节,抗炎和抗病毒特征.
这些特性表明MSCs可以减轻与SARS-CoV-2感染相关的细胞因子风暴.

结论:

介质细胞干细胞 (MSCs) 显示出作为孕妇COVID-19治疗策略的前景.
多重冠状病毒可能提供一种保护机制,防止怀孕期间SARS-CoV-2感染的严重后果.
对基于MSC的疗法进行进一步的研究对于COVID-19和未来的病毒爆发有必要.

关键词:

在 COVID-19 疫情中,多国中心的MSCs.这就是SARS-CoV-2病毒.怀孕怀孕怀孕怀孕怀孕移植移植移植移植

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相关概念视频

Mesenchymal Stem Cells

Mesenchymal Stem Cells

Mesenchymal stem cells (MSCs) are adult stem cells that can differentiate into most connective tissue cell types, except for hematopoietic cells, depending upon the source of MSCs. For example, bone-marrow-derived MSCs (BM-MSCs) can differentiate into osteocytes, hepatocytes, and pancreatic and neuronal cells. MSCs can be isolated from various sources such as bone marrow, placenta, adipose tissue, teeth, and Wharton’s jelly, a gelatinous substance in the umbilical cord. The ease of their...