白血病:流行病学,成像,危险因素和与年龄相关的大脑白质过强度的管理
Wen-Qing Huang1, Qing Lin2,3,4,5, Chi-Meng Tzeng6
1Department of Central Laboratory, Shanghai Children's Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China.
Journal of stroke
|June 5, 2024
概括
白血病 (LA),大脑中的白质异常,在老年人中很常见. 本综述总结了LA流行病学,成像,病理学,风险因素和干预措施,突出了研究不一致性.
科学领域:
- 神经学 神经学
- 放射学 放射学是一门学科.
- 公共卫生 公共卫生
背景情况:
- 白血病 (LA) 涉及MRI上的白质超强度,表明大脑组织异常.
- 从40年代开始临床检测到,LA在全球60岁以上的个人中非常普遍.
- LA呈现异质,具有各种类型的病变,其中一些可能是无害的.
研究的目的:
- 为提供白血病 (LA) 的概述.
- 总结有关LA流行病学,神经成像,病理学,风险因素和干预措施的当前知识.
主要方法:
- 审查关于白血病的现有文献.
- 综合有关LA流行病学,神经成像分类,病理特征,风险因素和潜在干预措施的信息.
主要成果:
- 这种LA的特点是图像呈现的多样化,并且在老年人群中普遍存在.
- 不一致的研究结果归因于研究设计,神经成像,样本大小和LA的复杂性质的变化.
- LA对大脑功能有潜在的有害影响,并增加了公共卫生负担.
结论:
- 需要进一步的研究来解决不一致性,并了解LA的多因素性质.
- 标准化的方法对于在LA研究中取得一致的结果至关重要.
- 了解LA风险因素和制定干预措施对于公共卫生至关重要.
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