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Updated: Jul 8, 2026

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塞拉斯特可以通过NF-κb信号通路减少小鼠中多壁碳纳米管引起的肺炎

Tao-Lin Qing1, Xuan-Yao Jiang1, Jin-Feng Li1

  • 1Department of Health Toxicology, Faculty of Naval Medicine, Naval Medical University, Shanghai, China.

Inhalation toxicology
|June 5, 2024
PubMed
概括

塞拉斯是一种天然的抗炎药物,通过向NF-κB通路来减少由多壁碳纳米管 (MWCNTs) 引起的肺炎. 这项研究突出了塞拉斯特的作用.

关键词:
塞拉斯特罗尔 (Celastrol) 是一种在NF-κB信号通路中.这是一种炎症炎症炎症炎症.多壁碳纳米管多壁碳纳米管

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相关概念视频

NF-κB-dependent Signaling Pathway02:26

NF-κB-dependent Signaling Pathway

The transcription factor NF-κB was discovered in 1986 in the lab of Nobel laureate Professor David Baltimore, for its interaction with the immunoglobulin light chain enhancer in B-cells. After more than three decades of study, it is now evident that NF-κB regulates the expression of over 100 genes. Most of these genes play an essential role in the innate and adaptive immune responses as well as the inflammatory responses of animals.
NF-κB-dependent Signaling Mechanism
The heterodimer of NF-κB...