使用多核酸酸酶和多胺寡核酸合成mRNA副产品的快速和可扩展的检测

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Updated: Jul 16, 2026

Protocol for the Solid-phase Synthesis of Oligomers of RNA Containing a 2'-O-thiophenylmethyl Modification and Characterization via Circular Dichroism
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Protocol for the Solid-phase Synthesis of Oligomers of RNA Containing a 2'-O-thiophenylmethyl Modification and Characterization via Circular Dichroism

Published on: July 28, 2017

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Francis Combes1, Thanh-Huong Bui1, Frida J Pettersson1

  • 1Department of Biotechnology and Nanomedicine, SINTEF, Trondheim, Norway.

RNA biology
|June 5, 2024
PubMed
概括

在mRNA生产过程中的降解会影响疫苗的疗效. 一种使用多核酸酶 (PNPase) 的新酶分析方法快速而灵敏地测量mRNA完整性,为现有方法提供了可扩展的替代方案.

关键词:
这就是PNPase.测试试验 测试试验 测试试验副产品 副产品 副产品高通量的高通量它们是mRNARNA.

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