身体圆度指数和美国成年人全因死亡率
Xiaoqian Zhang1,2, Ning Ma1,3, Qiushi Lin4
1Graduate School, Beijing University of Chinese Medicine, Beijing, China.
JAMA network open
|June 5, 2024
概括
身体圆度指数 (BRI) 在美国成年人中一直在增加,并显示了与全因死亡风险的U形关联. 较高和较低的BRI水平与死亡率的增加有关,这表明BRI是潜在的查工具.
科学领域:
- 公共卫生 公共卫生
- 流行病学 流行病学
- 生物统计学 生物统计学
背景情况:
- 肥胖,特别是内脏肥胖,是已知的死亡风险因素.
- 传统的人类测量措施无法充分评估脂肪分布.
- 身体圆度指数 (BRI) 为脂肪分布分析提供了更全面的指标.
研究的目的:
- 分析美国成年人BRI的时间趋势.
- 调查BRI与全因死亡率之间的关联.
主要方法:
- 利用了美国国家健康和营养检查调查 (NHANES) (1999-2018) 中32,995名美国成年人的数据.
- 将NHANES数据与死亡记录连接到2019年12月31日.
- 采用韦布尔回归来评估BRI和全因死亡率之间的关联,使用受限制的立方线来确定最佳切断线.
主要成果:
- 从1999年到2018年,一带一路计划平均每两年增加0.95%,女性,老年人和墨西哥裔美国人的增长更为.
- 在BRI和全因死亡率之间观察到U形的关联.
- 与中间五分之一 (4.5-5.5) 相比,BRI<3.4 (HR 1.25) 和BRI≥6.9 (HR 1.49) 的死亡风险增加.
结论:
- 在过去二十年中,在美国成年人中观察到BRI的日益增长的趋势.
- 证明了BRI和全因死亡率之间存在显著的U形关联.
- 建议BRI作为一种潜在的非侵入性查工具,用于评估公共卫生中的死亡风险.
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