性恶性瘤的生活质量结果
Anthony Tang1, Jinhong Li2, Nicole Scheff3
1University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, U.S.A.
The Laryngoscope
|June 5, 2024
概括
恶性瘤手术后的辅助化疗 (CRT) 和放射治疗 (RT) 与患者报告的结果较差有关. 这些包括生活质量,吞和疼痛,突出治疗对生存率的影响.
科学领域:
- 耳鼻喉科 耳鼻喉科 耳鼻喉科
- 头部和部手术 头部和部手术
- 在瘤学瘤学.
- 患者报告的结果
背景情况:
- 恶性瘤 (MPT) 需要手术干预,通常需要辅助疗法.
- 评估患者报告的结果指标 (PROM) 对于了解MPT治疗对生活质量的长期影响至关重要.
研究的目的:
- 为了评估患者报告的结果措施 (PROMs) 在患有恶性瘤手术 (MPT) 的患者中.
- 确定与MPT幸存者的PROM相关的临床因素,包括辅助疗法.
主要方法:
- 在头癌 (HNC) 生存诊所内,对手术治疗的MPT患者 (2017-2023) 的回顾性分析.
- 使用了验证的PROM:UW-QOL,EAT-10,PHQ-8,GAD-7,NDI和失眠严重程度指数.
- 多变量回归分析探索了PROMs的预测因素.
主要成果:
- 临床相关的消化不良,抑郁,焦虑,部疼痛和失眠的患病率分别在32.3%,15.5%,7.1%,17.7%和7.2%的患者中观察到.
- 与单独手术相比,辅助化疗放射治疗 (CRT) 和放射治疗 (RT) 与更差的身体生活质量 (QOL),社会情感QOL和吞得分有显著的关联.
- 接受CRT的患者也报告说,与接受RT的患者相比,手术后的部疼痛更严重.
结论:
- 在MPT手术后辅助CRT和RT与患者报告结果的减少有关.
- 这些发现强调了考虑辅助疗法对MPT患者生存率和生活质量的影响的重要性.
相关概念视频
01:26Assessment of the Mouth
171
A thorough mouth assessment, including inspection and palpation of the lips, gums, tongue, tonsils, uvula, and pharynx, is crucial in detecting potential health issues. Diseases ranging from oral cancer to systemic conditions like diabetes could be identified early through careful oral examination. This article provides a detailed guide on conducting a comprehensive mouth assessment.
Mouth Inspection
The inspection begins with visually examining the mouth for symmetry, color, and size.
Mouth Inspection
The inspection begins with visually examining the mouth for symmetry, color, and size.
171
01:26Tonsillitis II: Management
110
This lesson will focus on the different treatment options for managing tonsillitis, which typically depend on the cause and severity.
110
01:21Cancer Survival Analysis
343
Cancer survival analysis focuses on quantifying and interpreting the time from a key starting point, such as diagnosis or the initiation of treatment, to a specific endpoint, such as remission or death. This analysis provides critical insights into treatment effectiveness and factors that influence patient outcomes, helping to shape clinical decisions and guide prognostic evaluations. A cornerstone of oncology research, survival analysis tackles the challenges of skewed, non-normally...
343
01:23Chronic Pharyngitis
1.8K
Chronic pharyngitis refers to persistent inflammation of the pharyngial mucosa.
Etiology
It often arises from persistent viral or bacterial infections affecting sinuses and tonsils.
Additional contributing factors include inadequate dental hygiene, mouth breathing, recurring tonsillitis, allergic rhinitis, laryngopharyngeal reflux, and exposure to smoke, chemicals, and other environmental pollutants. Allergic reactions to pollen, mold, and pet dander, chronic cough, excessive voice usage,...
Etiology
It often arises from persistent viral or bacterial infections affecting sinuses and tonsils.
Additional contributing factors include inadequate dental hygiene, mouth breathing, recurring tonsillitis, allergic rhinitis, laryngopharyngeal reflux, and exposure to smoke, chemicals, and other environmental pollutants. Allergic reactions to pollen, mold, and pet dander, chronic cough, excessive voice usage,...
1.8K