干预后烧灼和的干预措施
Sarthak Sinha1, Vincent A Gabriel2, Rohit K Arora1
1Department of Comparative Biology and Experimental Medicine, University of Calgary, Calgary, Canada.
The Cochrane database of systematic reviews
|June 5, 2024
概括
烧后 () 是常见的,但21项干预的证据是中度到低确定性. 一些治疗方法,如多克西奶油和按摩,显示出潜在的益处,但需要更多高质量的研究.
科学领域:
- 皮肤病学 皮肤病学
- 基于证据的医学基于证据的医学.
- 临床试验 临床试验
背景情况:
- 烧伤后的 () 是烧伤后的常见和令人痛苦的症状.
- 目前治疗烧后的治疗方法缺乏有效性的明确证据.
- 本综述评估了在各种环境中管理烧后的干预措施.
研究的目的:
- 系统地评估各种干预措施治疗后烧的疗效.
主要方法:
- 在多个数据库和临床试验注册表中进行了全面的搜索,截至2022年9月.
- 包括25个随机对照试验 (RCT),评估了21种不同的干预措施.
- 使用GRADE方法评估证据的确定性.
主要成果:
- 神经调节剂 (多克西, gabapentin, 普雷加巴林, 丹塞) 显示低至中等确定性证据减少.
- 局部疗法,身体方式 (按摩,ESWT) 和激光痕修复也表现出了一些有效性,证据水平不同.
- 大多数被纳入的研究都是小的,具有偏差的高风险;次要结果往往没有报告.
结论:
- 对21项治疗烧后的干预措施的证据确定性中等至低.
- 虽然一些干预措施显示出希望,但证据的质量受到研究规模和偏见风险的限制.
- 实践者应仔细考虑现有中等确定性证据对患者的适用性.
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