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在2020-2023年期间,HPLC和UPLC (或UHPLC) 分析植物大麻素的进展

Lutfun Nahar¹, Phanuphong Chaiwut², Sarita Sangthong²

¹Laboratory of Growth Regulators, Palacký University and Institute of Experimental Botany, The Czech Academy of Sciences, Olomouc, Czech Republic.

Phytochemical analysis : PCA

|June 5, 2024

概括

高性能液态染色学 (HPLC) 和超高性能液态染色学 (UPLC/UHPLC) 对于分析植物性大麻素至关重要. 这些方法,通常与紫外线或质谱检测器相结合,在各种矩阵中的大麻素分析中仍然占主导地位.

科学领域:

分析化学分析化学
药理学是指药理学,它是指药理学.
法医科学法医科学法医科学

背景情况:

大麻素是与大麻素受体相互作用的有机分子,表现出与大麻素 L. sativa 的化合物相似的特性.
高性能液态染色学 (HPLC) 和超高性能液态染色学 (UPLC/UHPLC) 是检测和量化植物性大麻素的主要分析技术.
这些染色学方法通常与紫外线,光二极管阵列 (PDA) 或质谱 (MS) 探测器相结合.

研究的目的:

进行关于HPLC和UPLC/UHPLC方法用于植物大麻素分析的科学文献的批判性审查.
涵盖2020年1月至2023年12月期间发表的研究.

主要方法:

使用主要科学数据库 (Web of Science,PubMed,Google Scholar) 和相关书籍进行了详尽的文献搜索.
关键词包括各种各样的大麻素,大麻,大麻,大麻的组合,以及HPLC,UHPLC和UPLC等分析技术,以及定量,定性和质量控制分析的术语.

主要成果:

确定了许多基于HPLC和UPLC/UHPLC的植物大麻素分析方法.
常见的方法包括HPLC-UV和HPLC-PDA,越来越多地使用HPLC-MS,HPLC-MS/MS,UPLC/UHPLC-PDA,UPLC/UHPLC-MS和UPLC/UHPLC-MS/MS.
审查还指出了用于协议优化计算模型的应用,以及在样品准备中使用环保的提取技术.

结论:

在各种样本类型中,HPLC和UPLC/UHPLC仍然是确定植物性大麻素的主要分析方法.
这些技术对于大麻素科学领域的研究,质量控制和监管合规性至关重要.

关键词:

大麻sativa是一种大麻.美国HPLC,UPLC,UHPLC,大麻在HPLC-MS中.通过HPLC-MS/MS进行.这是一个HPLC-PDA.分析分析分析这是一种大麻素大麻素.检测检测检测检测检测哈希希哈希希哈希希哈希希哈希希哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈大麻大麻大麻大麻是什么意思这是一种植物性大麻素 (phytocannabinoid).精神药物精神药物是一种精神药物.质量控制质量控制质量控制这是一棵杂草.

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