心率变化和葡萄糖清除在健康男性和女性之间的关系
Abigail Nickel1, Robert Buresh1, Cherilyn McLester1
1Department of Exercise Science and Sport Management, Kennesaw State University, Kennesaw, Georgia, United States of America.
PloS one
|June 5, 2024
概括
像RMSSD和SDNN这样的休息心率变化 (HRV) 标志物与健康成年人的禁食血糖相关. 在口服葡萄糖耐受性测试 (OGTT) 中观察到HRV和葡萄糖代谢之间的性别特异关系.
科学领域:
- 生理学 生理学 生理学
- 代谢健康 代谢健康
- 自主神经系统功能 自主神经系统功能
背景情况:
- 心率变化 (HRV) 反映了自主神经系统 (ANS) 活动,影响新陈代谢调节.
- 了解HRV和葡萄糖代谢之间的相互作用对于代谢健康评估至关重要.
研究的目的:
- 量化休息HRV标记物与口服葡萄糖耐受性测试 (OGTT) 的反应之间的关系.
- 调查HRV与葡萄糖代谢之间的关系中的潜在基于性别的差异.
主要方法:
- 在18名健康成年人 (10名男性,8名女性) 中,休息HRV记录了10分钟.
- 分析了HRV的关键参数 (RMSSD,SDNN,HF,LF).
- 参与者接受了标准的2小时OGTT,在多个时间点测量葡萄糖.
主要成果:
- 休息HRV标志物 (RMSSD,SDNN,HF,LF) 与整体组的禁食血糖 (FBG) 有很强的相关性.
- 在曲线下的OGTT葡萄糖面积 (AUC) 和HRV标志物 (RMSSD,SDNN,LF) 之间仅在男性中发现了显著的相关性.
- 对于FBG,AUC或分析的HRV参数,没有观察到显著的性别差异.
结论:
- 休息自主活动,如HRV所示,与健康个体的禁食葡萄糖水平有关.
- 自主功能和葡萄糖耐受性之间存在性别特定的关联,特别是在男性中.
- 这些发现表明,自主神经系统和葡萄糖代谢之间存在微妙的关系,受性别的影响.
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