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Updated: Jun 23, 2026

Polymalic Acid-based Nano Biopolymers for Targeting of Multiple Tumor Markers: An Opportunity for Personalized Medicine?
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用于向药物输送的生物化治疗性两性聚氨

Sagar Bag1, Mandip Pratham Gadpayle2, Desoshree Ghosh1

  • 1Polymer Research Centre and Centre for Advanced Functional Materials, Department of Chemical Sciences, Indian Institute of Science Education and Research Kolkata, Nadia, Mohanpur, West Bengal 741246, India.

Biomacromolecules
|June 5, 2024
PubMed
概括

研究人员开发了可生物降解的纳米载体,使用刺激响应的聚合物进行药物输送. 这些新型聚氨对癌细胞具有选择性毒性,为向抗癌疗法提供了有前途的方法.

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Site-targeted drug delivery systems enhance therapeutic efficacy while minimizing systemic toxicity and treatment costs. Unlike conventional methods, these systems ensure precise drug delivery, improving bioavailability and reducing side effects. Targeted drug delivery is classified into three levels. First-order targeting directs drugs to the capillary beds of specific organs or tissues. Second-order targets specific cell types, such as tumor cells, using receptor-mediated interactions.
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