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Updated: Jun 24, 2025

Core/shell Printing Scaffolds For Tissue Engineering Of Tubular Structures
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通过主动喷嘴尺寸和形状控制进行多尺度3D打印.

Seok Won Kang1, Jochen Mueller1

  • 1Department of Civil and Systems Engineering, Johns Hopkins University, Baltimore, MD, USA.

Science advances
|June 5, 2024
PubMed
概括
此摘要是机器生成的。

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适应喷嘴3D打印 (AN3DP) 动态地改变喷嘴大小,以获得高分辨率和速度. 这一创新能够打印复杂的多尺度架构和先进的生物打印植入物.

科学领域:

  • 材料科学 材料科学 材料科学
  • 机械工程 机械工程
  • 生物医学工程 生物医学工程

背景情况:

  • 由于固定喷嘴直径,传统的3D打印面临着分辨率速度的权衡.
  • 这种限制阻碍了具有大量和复杂特征的多尺度架构的制造.

研究的目的:

  • 引入自适应喷嘴3D打印 (AN3DP) 进行动态喷嘴直径和形状控制.
  • 为了克服基于挤出的3D打印中的分辨率速度冲突.

主要方法:

  • 开发了一个AN3DP系统,在一个柔性膜周围有八个可控制的,肌驱动的针.
  • 优化喷嘴设计用于剪切稀释油墨和限制空间打印 (符合规范,嵌入式).

主要成果:

  • 证明了具有连续梯度的部件的制造,避免了离散.
  • 与传统3D打印相比,实现了更高的密度和轮精度.
  • 成功打印了具有骨状微型架构的细胞载荷和层次植入物.

结论:

  • AN3DP显著扩大了基于挤出的3D打印的能力.
  • 该技术有助于各种应用,包括先进的生物打印.

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Last Updated: Jun 24, 2025

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  • 通过AN3DP,可以创建以前无法实现的复杂,高精度结构.