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Updated: Jun 24, 2025

Strand-Specific Analysis of Proteins at Replicating DNA Strands by Enrichment and Sequencing of Protein-Associated Nascent DNA Method
08:53

Strand-Specific Analysis of Proteins at Replicating DNA Strands by Enrichment and Sequencing of Protein-Associated Nascent DNA Method

Published on: May 2, 2025

324

PCNA-Pol δ复合体对落后链DNA合成到父基因素转移用于表观遗传的遗传

Albert Serra-Cardona1, Xu Hua1, Seth W McNutt2

  • 1Institute for Cancer Genetics, Department of Pediatrics and Department of Genetics and Development, Columbia University Irving Medical Center, New York, NY 10019, USA.

Science advances
|June 5, 2024
PubMed
概括

父母组织激素H3-H4转移对于细胞身份至关重要. 这项研究揭示了DNA聚合酶Pol δ和PCNA调节这种基因素转移,将DNA合成与表观遗传结合起来.

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