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Updated: Jun 24, 2025

DNA Virus Detection System Based on RPA-CRISPR/Cas12a-SPM and Deep Learning
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DNA Virus Detection System Based on RPA-CRISPR/Cas12a-SPM and Deep Learning

Published on: May 10, 2024

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在Cas9和Cas12蛋白中识别家族特征:使用完整蛋白特征光谱的机器学习方法

Sita Sirisha Madugula1, Pranav Pujar2, Bharani Nammi2

  • 1Department of Pharmaceutical Sciences, University of North Texas System College of Pharmacy, University of North Texas Health Science Center, 3500 Camp Bowie Blvd, Fort Worth, Texas 76107, United States.

Journal of chemical information and modeling
|June 5, 2024
PubMed
概括

这项研究使用机器学习确定了独特的蛋白质特征,区分了Cas9和Cas12基因编辑蛋白与非Cas蛋白的区别. 这些已识别的特征可以指导对遗传疾病进行改进的CRISPR-Cas系统的开发.

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