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Updated: Jun 24, 2025

Use of Single Chain MHC Technology to Investigate Co-agonism in Human CD8+ T Cell Activation
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葡萄糖样1受体是一种T细胞阴性辅助刺激分子

Moufida Ben Nasr1, Vera Usuelli2, Sergio Dellepiane3

  • 1International Center for T1D, Pediatric Clinical Research Center Romeo ed Enrica Invernizzi, DIBIC, Università di Milano, Milan, Italy; Nephrology Division, Boston Children's Hospital, Harvard Medical School, Boston, MA, USA; Transplantation Research Center, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.

Cell metabolism
|June 5, 2024
PubMed
概括

葡萄糖类-1受体 (GLP-1R) 在T细胞上表达,并调节免疫反应. GLP-1R信号延长了异种移植的存活时间,并减少了免疫排斥,而其对抗作用促进了抗瘤免疫力.

关键词:
这是一个GLP-1RR.这是GLP-1R激动剂.在GLP-1R信号传输中.所有的豁免权.癌症 癌症 癌症 癌症 癌症免疫检查点是一个检查点.

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