功能失调的昼夜时钟加速了肠道微生物群的癌症转移,引发了骨髓衍生抑制细胞的积累

Jing-Lin Liu1, Xu Xu2, Youlutuziayi Rixiati2

  • 1Department of Pathology, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou 510120, China.

Cell metabolism
|June 5, 2024
PubMed
概括

昼夜节律和肠道细菌代谢物taurocholic 酸的干扰通过影响骨髓衍生抑制细胞 (MDSCs) 来促进结直肠癌 (CRC) 转移. 这项研究揭示了连接生物钟,肠道微生物群和癌症传播的系统机制.

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