2004年至2017年芬兰的十二指肠:流行率,死亡率和相关异常 - - 一项基于人口的研究
Suvi Alikärri1,2, Ilkka Helenius1,3, Susanna Heiskanen1
1Department of Paediatric Surgery, Orthopaedics and Traumatology, University of Turku and Turku University Hospital, Turku, Finland.
概括
芬兰的十二指肠缩症 (DA) 患病率稳定且高,心脏异常显著增加死亡风险. 尽管存在相关疾病,但十二指腺缩的总体存活率仍然很高.
科学领域:
- 儿科手术 儿科手术
- 遗传异常是一种先天性异常.
- 公共卫生流行病学 流行病学
背景情况:
- 十二指肠缩 (DA) 是最常见的小肠缩形式.
- 了解DA的流行病情景对于资源分配和临床管理至关重要.
- 此前对芬兰的阿尔茨海默病患病率和相关因素的研究是有限的.
研究的目的:
- 为了确定芬兰十二指肠缩症 (DA) 的患病率.
- 调查与DA相关的死亡率.
- 为了识别与DA经常同时发生的先天性异常.
主要方法:
- 一项全国性的回顾性研究,利用芬兰卫生与福利研究所和芬兰统计局的记录.
- 包括2004年至2017年所有活产,死产和终止妊娠的情况.
- 通过ICD-9和ICD-10代码识别病例;使用EUROCAT标准对异常进行分类,不包括小异常.
主要成果:
- 总共有249个DA病例被确定,活产患病率为2.75/10,000例.
- 相关异常很常见,包括心脏缺陷 (36.1%) 和三形21 (25.3%).
- 新生儿死亡率为3.6%,心脏异常是显著的危险因素 (p < 0.001).
结论:
- 在芬兰,十二指甲状腺缺血的患病率稳定且显著高.
- 心脏异常与DA患者的死亡率增加密切相关.
- 尽管存在相关异常,但十二指甲状腺缩的整体生存率是有利的.
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