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相关概念视频

The Bone Matrix01:18

The Bone Matrix

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Bone contains a relatively small number of cells entrenched in a matrix of collagen fibers that provide an adherent surface for inorganic salt crystals. Both components of the matrix, organic and inorganic, contribute to the unusual properties of bone. Without collagen, bones would be brittle and shatter easily. Without mineral crystals, bones would flex and provide little support. This can be observed by an experiment: when the minerals of a bone are dissolved by soaking the bone in...
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Essential Minerals for Bone Health01:31

Essential Minerals for Bone Health

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The minerals contained in all of the food we consume are essential for our organ systems. However, certain essential minerals, such as calcium, phosphorus, magnesium, manganese, and fluoride, largely affect bone health.
Calcium and Phosphorus
Calcium is a critical component of bones, especially in the form of calcium phosphate and calcium carbonate. Since the body cannot make calcium, it must be obtained from the diet. However, calcium cannot be absorbed from the small intestine without...
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Structure and Function of Platelets01:18

Structure and Function of Platelets

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The cell fragments known as platelets are disc-shaped, with an average diameter of about 3 μm and a thickness of roughly 1 μm. They play a crucial role in the body's vascular clotting system, which also involves plasma proteins, blood cells, and blood vessel tissues.
Platelets are continually replenished, circulating in the bloodstream for 9-12 days before being removed by phagocytes, primarily in the spleen. A microliter of circulating blood contains between 150,000 and 450,000...
1.1K
Spongy Bone01:09

Spongy Bone

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All bones comprise an outer layer of compact bone, and an interior made up of spongy bone tissue, also called cancellous or trabecular bone. In long bones, spongy bone tissue is mainly found in the interior of the epiphyses (broad ends of the bone).
Spongy bone is more porous, and less dense compared to compact bone. It is composed of concentric lamellae that are arranged irregularly to form the trabecular network. In some bones, the spaces between trabeculae contain red marrow, where...
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Compact Bone01:27

Compact Bone

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Most bones contain compact and spongy osseous tissue, but their distribution and concentration vary based on the bone's overall function.
Compact bone, also called cortical bone, is the denser, stronger of the two types of bone tissue. It is found under the periosteum and in the diaphyses of long bones, where it provides support and protection. The microscopic structural unit of compact bone is called an osteon, or haversian system. Each osteon is composed of concentric rings of calcified...
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Bone as Supporting Connective Tissue01:23

Bone as Supporting Connective Tissue

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Bone tissue forms the internal skeleton of vertebrate animals, providing structure to the body.
Bone Matrix
Bone, or osseous tissue, is a connective tissue that has a large amount of two different types of matrix material. The organic matrix is similar to the matrix material found in other connective tissues, including some amount of collagen and elastic fibers. This gives strength and flexibility to the tissue. The inorganic matrix consists of mineral salts— mostly calcium salts—...
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相关实验视频

Updated: Jun 24, 2025

Analysis of Minerals Produced by hFOB 1.19 and Saos-2 Cells Using Transmission Electron Microscopy with Energy Dispersive X-ray Microanalysis
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Analysis of Minerals Produced by hFOB 1.19 and Saos-2 Cells Using Transmission Electron Microscopy with Energy Dispersive X-ray Microanalysis

Published on: June 24, 2018

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在骨中曲的矿物质血小板.

H P Schwarcz1, Nadine Nassif2, Viktoria Kovacs Kis3

  • 1School of Earth, Environment and Society, McMaster University, Hamilton, Ontario, Canada; School of Biomedical Engineering, McMaster University, Hamilton, Ontario, Canada.

Acta biomaterialia
|June 5, 2024
PubMed
概括

骨头 骨头 骨头 骨头

关键词:
无情的人是无情的.可开发的表面可开发.折叠可以折叠.离子束磨削 离子束磨削堆 堆 堆 堆传输电子显微镜的使用

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In Vivo Two-photon Imaging of Megakaryocytes and Proplatelets in the Mouse Skull Bone Marrow
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In Vivo Two-photon Imaging of Megakaryocytes and Proplatelets in the Mouse Skull Bone Marrow

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Proplatelet Formation Dynamics of Mouse Fresh Bone Marrow Explants
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Proplatelet Formation Dynamics of Mouse Fresh Bone Marrow Explants

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相关实验视频

Last Updated: Jun 24, 2025

Analysis of Minerals Produced by hFOB 1.19 and Saos-2 Cells Using Transmission Electron Microscopy with Energy Dispersive X-ray Microanalysis
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Analysis of Minerals Produced by hFOB 1.19 and Saos-2 Cells Using Transmission Electron Microscopy with Energy Dispersive X-ray Microanalysis

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In Vivo Two-photon Imaging of Megakaryocytes and Proplatelets in the Mouse Skull Bone Marrow
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In Vivo Two-photon Imaging of Megakaryocytes and Proplatelets in the Mouse Skull Bone Marrow

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科学领域:

  • 生物材料科学 生物材料科学
  • 结构生物学 结构生物学
  • 生物物理学的生物物理.

背景情况:

  • 骨头是一种复合材料,主要由原纤维和矿物酸盐组成.
  • 已知骨的矿物成分存在于大约5纳米厚的平面多晶血小板中.
  • 这些矿物质血小板被组织成堆,但它们的精确排列和对骨机械性质的贡献仍然是研究领域.

研究的目的:

  • 为了研究骨中矿物质血小板的三维结构.
  • 阐明矿物质血小板形态和原纤维之间的关系.
  • 了解观察到的矿物质结构如何促进骨的机械强度.

主要方法:

  • 使用传输电子显微镜 (TEM) 检查骨微观结构.
  • 分析的重点是矿物质血小板相对于原纤维的方向和曲率.

主要成果:

  • 骨的矿物质酸盐血小板不是平的,而是弧形的片段,弧度半径从25纳米到数百纳米.
  • 这些曲的血小板形成2到30多个的堆,并与原纤维轴平行方向.
  • 矿物质血小板的曲率允许它们在原纤维周围编织,增强骨的压力强度.

结论:

  • 骨的矿物成分组织成曲的血小板,而不是以前认为的平坦的.
  • 矿物质血小板的这种新曲线形态对于骨的结构完整性和机械弹性至关重要.
  • 了解这些纳米级结构特征为骨生物力学提供了新的见解.