新生儿和母亲的 Ichthyosiform 皮肤病与 Kava 在怀孕期间的使用相关
Hannah H Spungen1,2, Kartik Mody1,2,3, Becky Micetic2,3
1University of Arizona College of Medicine- Phoenix, Phoenix, AZ, USA.
概括
孕妇在怀孕期间使用卡瓦可能会导致一种罕见的新生儿皮肤疾病,称为获得性 Ichthyosis. 这一案例凸显了教育孕妇有关卡瓦卡瓦的重要性.
科学领域:
- 围产儿医学 围产儿医学
- 皮肤病学 皮肤病学
- 药理学 药理学是指药理学的学科.
背景情况:
- 卡瓦 (Piper methysticum) 越来越受欢迎,用于缓解焦虑和疼痛.
- 雄状皮肤病是一种已知的成人副作用,但在母亲使用的新生儿中以前没有描述过.
- 这项研究解决了在怀孕期间了解卡瓦的影响方面的差距.
研究的目的:
- 描述一个新生儿胆形皮肤病的病例,可能与孕妇在怀孕期间食用卡娃有关.
- 为了提高人们对卡瓦在孕妇中使用的风险的认识.
- 为了解胎儿暴露风险做出贡献.
主要方法:
- 一个孕妇在整个孕期使用卡瓦/克拉托姆产品的案例报告.
- 观察母亲和新生儿的临床表现,包括皮肤学发现.
- 产后随访婴儿的皮肤和整体健康状况.
主要成果:
- 母亲患上了 Ichthyosiform 皮肤病,产后得到了缓解.
- 婴儿呈现出扩散性 ichthyosiform 皮疹,类似于成人 kava 皮肤病,以及新生儿阿片类药物戒断综合征.
- 婴儿的皮疹在第22天就消失了,在9个月的随访中没有复发.
结论:
- 孕妇在怀孕期间使用卡瓦可能会导致胎儿获得的 Ichthyosis.
- 提高公众对卡瓦在怀孕期间潜在的不良影响的认识至关重要.
- 这一案例强调了在怀孕期间使用草药补充剂时需要谨慎.
相关概念视频
Parental Care
Many animals exhibit parental care behavior, including feeding, grooming, and protecting young offspring. Parental care is universal in mammals and birds, which often have young that are born relatively helpless. Several species of insects and fish, as well as some amphibians, also care for their young.
Teratogenicity
The ability of a drug to produce structural deformations and functional abnormalities in the developing embryo or the fetus is called teratogenicity, and the drug producing this effect is known as a teratogen. Teratogenic effects include stillbirth, miscarriage, intrauterine growth restriction, and neurocognitive delay. A teratogen may affect the embryo at different stages of development, which is important in determining the type and extent of the damage. During blastocyst formation, the early...
Upper Respiratory Drugs: Antitussives, Expectorants, and Mucolytics
Respiratory symptoms, such as congestion and cough, commonly accompany respiratory tract conditions. Various medications, such as antitussives, expectorants, and mucolytics, play crucial roles in providing relief.
Antitussives include codeine, dextromethorphan (Robitussin), and benzonatate (Tessalon). Codeine and dextromethorphan exert their effects centrally by suppressing the cough reflex center in the medulla. Benzonatate operates peripherally within the respiratory tract by anesthetizing...
Antitussives include codeine, dextromethorphan (Robitussin), and benzonatate (Tessalon). Codeine and dextromethorphan exert their effects centrally by suppressing the cough reflex center in the medulla. Benzonatate operates peripherally within the respiratory tract by anesthetizing...
Development of Human Microbiota
The human microbiota begins developing at birth and undergoes continual change as we age. Infancy marks a critical period of microbial sensitivity, offering a “window of opportunity” during which beneficial microbes help mature the immune system. By age three, children typically develop a more stable and diverse microbial community. Newborns acquire microbes from their immediate environment; vaginal delivery favors maternal vaginal microbes, while cesarean births favor microbes from the skin...
Development of the Oral Microbiota
The establishment of the oral microbiome begins before birth, challenging the long-held belief that the fetal oral cavity is sterile. The presence of oral microbes such as Streptococcus and Fusobacterium in amniotic fluid suggests that microbial exposure may occur in utero, potentially through translocation from the maternal oral or gastrointestinal tract. This early colonization primes the neonatal immune system and sets the stage for subsequent microbial succession. Maternal health,...


