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Updated: Jun 24, 2025

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人类长链乙-CoA脱酶和相关乙-CoA脱酶的扩展基质特异性的结构基础

Beena Narayanan1, Chuanwu Xia2, Ryan McAndrew1,3

  • 1Department of Biochemistry, Medical College of Wisconsin, 8701 Watertown Plank Road, Milwaukee, WI, 53226, USA.

Scientific reports
|June 5, 2024
PubMed
概括

晶体结构显示,人类的长链乙-CoA脱酶 (LCAD) 结合了重的基质,这表明其作用超出了脂肪酸氧化. 这一发现将LCAD与ACAD10和ACAD11重新分类为一个不同的酶类.

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