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Updated: Jun 24, 2025

A Computerized Test Battery to Study Pharmacodynamic Effects on the Central Nervous System of Cholinergic Drugs in Early Phase Drug Development
07:02

A Computerized Test Battery to Study Pharmacodynamic Effects on the Central Nervous System of Cholinergic Drugs in Early Phase Drug Development

Published on: February 11, 2019

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主要使用适应性设计,但在早期药物试验阶段报告不足

Yuning Wang1,2,3, Minghong Yao1,2,3, Jiali Liu1,2,3

  • 1Institute of Integrated Traditional Chinese and Western Medicine, West China Hospital, Chinese Evidence-based Medicine Center and Chinese Cochrane Center, Sichuan University, Chengdu, 610041, China.

BMC medical research methodology
|June 5, 2024
PubMed
概括

适应性设计在药物试验中越来越多地用于提高效率,但报告质量仍然不理想. 需要进一步努力,以提高适应性试验报告的透明度和完整性,以改善药物开发.

关键词:
适应性设计适应性设计集团顺序设计 集团顺序设计随机对照试验是随机对照试验.报告质量报告质量

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