损伤的决定因素和危险因素:因严重的精神性厌食症住院的患者的情况如何? 一个多中心的研究
Chantal Stheneur1,2,3, Corinne Blanchet4,5, Lama Mattar6
1University Center for Adolescent and Young Adult Health, Fondation Santé des Etudiants de France, 75014, Paris, France. chantal.stheneur@fsef.net.
Journal of eating disorders
|June 5, 2024
概括
严重的神经性厌食症 (AN) 的损伤很常见,即使不是由于脱水. 下肢体质量指数 (BMI) 与AN患者功能障碍的严重程度直接相关.
科学领域:
- 腎臟病學 (nephrology) 是一種醫學專業.
- 精神病学是一个精神病学.
- 内部医学 内部医学
背景情况:
- 脏损伤是厌食症 (AN) 患者的一个未被认可的并发症,通常仅归因于脱水.
- 这项研究调查了患有AN的住院青少年和成年人病的患病率,严重程度和风险因素.
研究的目的:
- 为了确定患有神经性厌食症的患者功能障碍的频率和程度.
- 为了确定与AN患者脏干扰相关的危险因素.
主要方法:
- 一项多中心研究涉及197名来自住院饮食障碍病房的参与者 (13-65岁).
- 收集的数据包括AN史,临床特征,生物标志物和药物.
主要成果:
- 入院时的平均BMI为13.1kg/m2,平均年龄为20.74岁.
- 检测到功能障碍,平均估计的淋巴膜过率 (eGFR) 为74.74毫升/分钟;2%的参与者有eGFR<45毫升/分钟.
- 入院时的体重指数 (BMI) 是功能障碍的唯一决定因素,较低的BMI表明更严重的脏问题.
结论:
- 估计的淋巴膜过率 (eGFR) 计算显示严重的精神性厌食症需要住院治疗的严重功能障碍.
- 营养不良的严重程度,以低BMI表示,是功能障碍的独立风险因素.
- 常规功能测试,包括与肌素一起的eGFR,建议AN患者检测潜在的功能障碍.
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