抗生素在受影响下第三手术后的预防性有效性
Rongxin Sun1, Xiaojie Zhang1, Xiaolong Zang1
1Department of Oral and Maxillofacial Surgery, Zhejiang University School of Medicine, Stomatology Hospital, Hangzhou, China.
概括
在受冲击的下第三提取后,不需要预防性抗生素. 较长的手术时间和患有脊髓炎的病史会对康复产生负面影响,增加了对止痛药的需求.
科学领域:
- 口腔和牙面部外科手术
- 牙科研究 牙科研究
背景情况:
- 手术切除受冲击的下第三是常见的.
- 预防性抗生素的必要性,以防止术后并发症是有争议的.
- 影响复苏的风险因素需要进一步调查.
研究的目的:
- 评估抗生素在影响下第三手术后减少手术后感染的预防性疗效.
- 确定影响术后康复的潜在风险因素.
主要方法:
- 一项涉及330名患者的队列试验,这些患者接受了受冲击的下第三骨提取.
- 患者被分为两组:一个接受抗生素,一个控制组.
- 主要结局是手术后感染;次要结局包括止痛药的摄入量,手术时间,患有腹膜炎的病史和伤口关闭.
主要成果:
- 手术后感染发生在3.64%的病例中,在抗生素 (3.01%) 和对照 (4.27%) 组 (p=0.54) 中的发病率相似.
- 止痛药的摄入量在两组之间是可比的 (p=0.16).
- 加长的手术时间 (≥15分钟) 和患有炎的病史与更高的止痛药使用有关 (p<0.05).
结论:
- 预防性抗生素不适用于预防手术后感染或减少在受冲击的下第三提取后缓解疼痛的需求.
- 手术时间和心膜炎史是影响术后康复和止痛药需求的重要因素.
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