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Updated: Jun 24, 2025

Isolation, Culture, and Characterization of Primary Dermal Fibroblasts from Human Keloid Tissue
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Isolation, Culture, and Characterization of Primary Dermal Fibroblasts from Human Keloid Tissue

Published on: July 28, 2023

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STAT3诱导的lncRNAGNAS-AS1通过在反循环中调解miR-196a-5p/CXCL12/STAT3轴来加速 keloid 形成

Yun Liu1, Teng-Xiao Ma1, Peng-Fei Fan1

  • 1Department of Plastic and cosmetic Surgery, Hainan General Hospital (Hainan Affifiliated Hospital of Hainan Medical University), Haikou, Hainan, China.

Experimental dermatology
|June 6, 2024
PubMed
概括

这项研究揭示了一个STAT3/GNAS-AS1/miR-196a-5p/CXCL12反循环,通过增加纤维细胞增殖,迁移和细胞外矩阵积累来驱动 keloid 进展.

关键词:
在CXCL12中,CXCL12是最重要的.在GNAS-AS1中.在STAT3中,我们可以使用STAT3.凯洛伊德 (Keloid) 是一种类型的物质.miR‐196a‐5p 的使用情况.

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