产前炎症住院趋势,风险因素和相关不良结果:一项回顾性队列研究
Christy Gandhi1, Timothy Wen2, Lilly Y Liu1
1Department of Obstetrics and Gynecology, Columbia University Irving Medical Center, New York, New York, USA.
概括
在美国,产前炎症住院病例正在减少. 然而,这些病例显示出在怀孕期间败血症和严重孕产妇发病率的风险上升.
科学领域:
- 产科和妇科 产科和妇科
- 传染性疾病 传染性疾病
- 公共卫生 公共卫生
背景情况:
- 产前炎症,怀孕期间的脏感染,对母亲和胎儿都有风险.
- 了解趋势和结果对于改善孕产妇保健至关重要.
- 之前的研究表明发生率和风险因素各不相同.
研究的目的:
- 分析美国产前炎症住院病例的趋势.
- 确定与这些住院相关的风险因素.
- 评估不良结果,包括败血症和严重的孕产妇发病率.
主要方法:
- 使用全国再接收数据库 (2010-2020) 进行的回顾性队列研究.
- 美国分娩住院病例的分析,先前诊断出产前炎症.
- 使用后勤回归和Joinpoint回归来评估趋势和风险.
主要成果:
- 从2010年到2020年,在产前炎症住院患者的数量下降了29%.
- 尽管下降,但败血症诊断的风险显著增加 (AAPC 17.2%).
- 在此期间,严重孕产妇死亡率的风险也增加了 (AAPC5.5%).
结论:
- 在美国,产前炎症住院病例正在下降.
- 与这些住院病例相关的败血症和严重孕产妇死亡率的风险增加令人担忧.
- 持续监测和改进的管理策略是有必要的.
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