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Updated: Aug 12, 2026

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建立和描述六种犬肝细胞癌细胞系

Ja Young Lee1, Kieun Bae1,2, Jung-Hyun Kim2,3

  • 1Department of Veterinary Biochemistry, College of Veterinary Medicine, Konkuk University, Seoul, Republic of Korea.

Frontiers in veterinary science
|June 6, 2024
PubMed
概括

建立了新的犬肝细胞癌 (HCC) 细胞系,显示出开发新疗法策略的前景. 这些模型有助于理解狗和人类的HCC瘤生物学和治疗反应.

关键词:
癌症细胞系癌症细胞系狗的肝细胞癌 (hepatocellular carcinoma) 是一种肝细胞癌.狗狗狗狗狗狗狗狗狗狗狗狗狗狗狗狗狗狗狗狗狗狗狗狗狗狗狗狗狗狗狗狗狗狗狗狗狗狗狗狗狗狗狗狗狗狗狗狗索拉芬尼布 (Sorafenib) 是一个这样一来,我们就有了ceranib.

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Cell Lines01:16

Cell Lines

A cell line is a population of cells grown in vitro that can be subcultured over several generations. Normal cells cease to divide after a certain number of cell divisions, a process known as replicative senescence. This number, called the Hayflick limit, was conceptualized by Leonard Hayflick in 1961 when he observed that fetal cells grown in culture could only divide 40-60 times. This limit is due to the shortening of the telomeres during each round of cell division, preventing cell division...