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Updated: Jun 24, 2025

Dissection of Larval Zebrafish Gonadal Tissue
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经典的遗传和荷尔蒙开关在胎儿的性别发育和超越期间

Paul-Martin Holterhus1, Alexandra Kulle1, Hauke Busch2

  • 1Christian-Albrechts University of Kiel (CAU) Pediatric Endocrinology and Diabetes, Department of Pediatrics I Kiel Germany.

Medizinische Genetik : Mitteilungsblatt des Berufsverbandes Medizinische Genetik e.V
|June 6, 2024
PubMed
概括

人类胎儿的性别发展涉及关键的遗传和荷尔蒙开关. 最近的发现揭示了性别发育 (DSD) 的生物差异范围,超出了简单的二进制系统.

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Development of the reproductive organs in an embryo starts from a bipotential state. This means the early embryo can develop either male or female reproductive organs. The formation of these organs begins with the growth of gonadal ridges that arise from the intermediate mesoderm during the fifth week of development.
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The Y chromosome is a sex chromosome found in several vertebrates and mammals, including humans. In addition to 22 pairs of autosomes, the human males have one X chromosome and one Y chromosome. In these organisms, the presence or absence of the Y chromosome determines the development of male traits.
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